Abstract BACKGROUND: Private healthcare is choice of point of care for 70% of Indians. Multidrug resistant tuberculosis (MDR-TB) treatment is costly and involves duration as long as 2…

Continue Reading Catastrophic costs of treating drug resistant tb patients in a tertiary care hospital in India

Abstract The World Health Organization launched a global initiative, known as aDSM (active TB drug safety monitoring and management) to better describe the safety profile of new treatment…

Continue Reading Surveillance of adverse events in the treatment of drug-resistant tuberculosis: A global feasibility study.

Abstract BACKGROUND: Interstitial lung disease (ILD) is a common manifestation of systemic sclerosis and a leading cause of systemic sclerosis-related death. Nintedanib, a tyrosine kinase inhibitor, has been…

Continue Reading Nintedanib for Systemic Sclerosis–Associated Interstitial Lung Disease

Abstract BACKGROUND: The increased incidence of drug-resistant TB is a major challenge for effective TB control. Limited therapeutic options and poor treatment outcomes of DR-TB may increase drug-resistance…

Continue Reading Towards tailored regimens in the treatment of drug-resistant tuberculosis: a retrospective study in two Italian reference Centres

Abstract Central nervous system tuberculosis (TB) is devastating and affects vulnerable populations. Multidrug (MDR-) and extensively drug resistant-tuberculous meningitis (TBM), specifically, is nearly uniformly fatal, with little information…

Continue Reading Delamanid Central Nervous System Pharmacokinetics in Tuberculous Meningitis in Rabbits and Humans.

Abstract The emergence of antimicrobial resistance against Mycobacterium tuberculosis, the leading cause of mortality due to a single microbial pathogen worldwide, represents a growing threat to public health…

Continue Reading Drug-resistant tuberculosis: An update on disease burden, diagnosis and treatment.

Abstract BACKGROUND: Tuberculosis (TB) remains the most common cause of infectious disease deaths worldwide. What is perhaps less appreciated is that the caseload of tuberculosis patients in South…

Continue Reading Tuberculosis in South Asia: a tide in the affairs of men.

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Continue Reading Bronchoalveolar lavage contamination by sterile containers: A unique and unrecognized cause of a false-positive galactomannan.

Abstract Progressive fibrotic interstitial lung diseases (ILDs) are characterised by major reductions in quality of life and survival and have similarities to certain malignancies. However, palliative care expertise…

Continue Reading Palliative care in interstitial lung disease: living well.

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Continue Reading A Standardized Diagnostic Ontology for Fibrotic Interstitial Lung Disease. An International Working Group Perspective.